The present disclosure relates to pharmaceutical composition for use in the maintenance of joint health in mammals, preferably humans. The disclosed composition is stable, nontoxic and comprises natural active ingredients having anti-inflammatory, lubricating, and pain-relieving properties. In an aspect, the present disclosure provides a composition for joint health that comprises a combination of fish oil, curcumin, boswellia extract, and sodium hyaluronate as active ingredients. In preferred embodiment, the disclosed composition can further include piperine as bioavailability enhancer. Compositions provided by the embodiments of the present disclosure support joint health, mobility and flexibility by alleviating joint pain and inflammation.
