Stanford Burnham Prebys Medical Discovery Institute
发明人:
Hongbo Pang,Erkki Ruoslahti
申请号:
US16607043
公开号:
US20200190142A1
申请日:
2018.05.01
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Disclosed are compositions and methods useful for targeting molecules to activated macrophages, such as tumor associated macrophages. The compositions and methods are based on peptide sequences, such as AMT peptides, that home to activated macrophages. The disclosed homing to activated macrophages is useful for delivering therapeutic and detectable agents to cells and tissues where immune system effects or inflammation are occurring.