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Compositions of a peptide targeting system for treating cancer
专利权人:
Inc.;PeptiMed
发明人:
Primiano, Thomas,Chang, Bey-Dih,Heidel, Jeremy
申请号:
AU2011323508
公开号:
AU2011323508A1
申请日:
2011.11.01
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
This invention describes a protein nanoparticle system for targeting siRNA or other drugs into tumors. The basis of the protein system is elastin-like peptides that self-assemble once exposed to the nucleic acid of the siRNA. Specific targeting peptides are fused to the core ELP structure by standard genetic engineering techniques. These targeting peptides confer specific binding of the nanoparticle to receptors on the surface of tumor cells and allow for uptake of the nanoparticle into the tumor cells.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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