The present disclosure is directed to methods for supporting resistance to bacterial growth in the gastrointestinal tract of a subject, particularly in that of a human infant. In certain embodiments, the method comprises administering to a subject a nutritional composition that has a low buffer strength, wherein administration of said nutritional composition decreases the bacterial counts of bacteria selected from the group consisting of Enteropathogenic E. coli (EPEC), Enteroaggregative E. coli (EAEC), Cronobacter sakazakii, Salmonella enterica, and combinations thereof in the subject’s gastrointestinal tract. This disclosure further relates to the manufacture and use of low-buffer nutritional compositions in methods for modulating gastric acidity and/or in methods for enhancing the rate of gastric emptying in a subject, each method comprising a step of administering at least one of said low-buffer nutritional compositions to the subject.本發明針對用於支持對抗個體之胃腸道(尤其是在人類嬰兒個體之胃腸道)中細菌生長的方法。於某些實施態樣中，該方法包含對個體投與具有低緩衝力之營養組成物，其中投與該營養組成物會減少該個體胃腸道中選自下列所組成之群組的細菌之細菌計數：腸致病性大腸桿菌(Enteropathogenic E.coli)(EPEC)、腸聚集性大腸桿菌(Enteroaggregative E.coli)(EAEC)、阪崎腸桿菌(Cronobacter sakazakii)、腸道沙門氏菌(Salmonella enterica)、及彼等之組合。本發明進一步關於製造低緩衝營養組成物及低緩衝營養組成物於調節個體內胃酸度之方法及/或增進個體內胃排空速率之方法中的用途，各方法包含對該個體投與至少一種該低緩衝營養組成物的步驟。
