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RIFAMYCIN DERIVATIVES
专利权人:
发明人:
GIUSEPPE CLAUDIO VISCOMI,MANUELA CAMPANA,MAHENA FOLEGATTI,VINCENZO CANNATA,PAOLO RIGHI,GOFFREDO ROSINI
申请号:
IN7692/CHENP/2011
公开号:
IN2011CN07692A
申请日:
2011.10.20
申请国别(地区):
IN
年份:
2013
代理人:
摘要:
Disclosed are compounds including rifamycin derivatives having antibacterial activities wherein the compounds have the following general formula (I) wherein: R is hydrogen or acetyl R1 and R2 are independently selected from the group consisting of hydrogen( C1-4) alkyl benzyloxy mono- and di-(C1-3) alkylamino-(C1-4)alkyl(C1-3)alkoxy(C1-4) alkyl hydroxy-methyl hydroxy-(C2-4)-alkyl and nitro or R1 and R2 taken together with two consecutive carbon atoms of the pyridine nucleus form a benzene ring optionally substituted by one or two methyl or ethyl groups and R3 is hydroxyalkyl (C1-4). In addition processes to obtain these compounds are described. The compounds have antibacterial activity.
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