CAMPANA MANUELA,FOLEGATTI MAHENA,CANNATA VINCENZO,RIGHI PAOLO,ROSINI GOFFREDO,VISCOMI GIUSEPPE CLAUDIO
申请号：
TN2011000265
公开号：
TN2011000265A1
申请日:
2011.05.24
申请国别(地区):
TN
年份:
2012
代理人:
摘要：
Disclosed are compounds including rifamycin derivatives having antibacterial activities, wherein the compounds have the following general formula (I) wherein: R is hydrogen or acetyl R1 and R2 are independently selected from the group consisting of hydrogen, ( C1-4) alkyl, benzyloxy, mono- and di-(C1-3) alkylamino-(C1-4)alkyl, (C1-3)alkoxy, (C1-4) alkyl, hydroxy-methyl, hydroxy-(C2-4)-alkyl, and nitro or R1 and R2 taken together with two consecutive carbon atoms of the pyridine nucleus form a benzene ring optionally substituted by one or two methyl or ethyl groups and R3 is hydroxyalkyl (C1-4). In addition, processes to obtain these compounds are described. The compounds have antibacterial activity.
