THE BRIGHAM AND WOMEN'S HOSPITAL; INC.;THE BRIGHAM AND WOMENS HOSPITAL
发明人:
FEINBERG, MARK W.,SUN, XINGHUI
申请号:
EP11754023
公开号:
EP2544703A4
申请日:
2011.03.09
申请国别(地区):
EP
年份:
2013
代理人:
摘要:
Provided are methods of treating or delaying the onset of a vascular inflammatory disease (e.g., acute lung injury) in a subject including administering to the subject a therapeutically effective amount of a nucleic acid containing all or a part of the sequence of mature miR-181b (SEQ ID NO: 1). Also provided are methods of decreasing nuclear factor-P² (NF-P²) signaling in an endothelial cell including administering to the subject a nucleic acid containing all or a part of the sequence of mature miR-181b (SEQ ID NO: 1).