LAI, HENRY, C.,SASAKI, TOMIKAZU,SINGH, NARENDRA, P.
申请号:
HK05110544.5
公开号:
HK1076055B
申请日:
2005.11.22
申请国别(地区):
HK
年份:
2012
代理人:
摘要:
In one aspect, the invention provides covalent conjugates between artemisinin-related endoperoxides and iron-carrying proteins. In some embodiments, the covalent conjugates comprise artelinate and holotransferrin. In another aspect, the invention provides methods for administering the covalent conjugates of the invention to treat cancer and infections by pathogens that bind iron-carrying proteins.