MERCK SHARP & DOHME CORP.;ALECTOS THERAPEUTICS INC.
发明人:
CHANG, JIANG,LIU, KUN,MCEACHERN, ERNEST J.,MU, CHANG-WEI,SELNICK, HAROLD G.,SHI, FENG,VOCADLO, DAVID J.,WANG, YAO-DE,WEI, ZHONGYONG,ZHOU, YUANXI,ZHU, YONGBAO
申请号:
TW100140566
公开号:
TW201249848A
申请日:
2011.11.07
申请国别(地区):
TW
年份:
2012
代理人:
摘要:
The invention is directed to compounds for selectively inhibiting glycosidases, uses of the compounds and pharmaceutical compositions including the compounds, and methods of treating diseases and disorders related to deficiency or overexpression of O-GlcNAcase, and/or accumulation or deficiency of O-GlcNAc.