MERCK SHARP & DOHME CORP.;ALECTOS THERAPEUTICS INC.
发明人:
LI, TONG-SHUANG,MCEACHERN, ERNEST J.,VOCADLO, DAVID J.,ZHOU, YUANXI,ZHU, YONGBAO,SELNICK, HAROLD G.
申请号:
EP12805186
公开号:
EP2726492A4
申请日:
2012.06.27
申请国别(地区):
EP
年份:
2015
代理人:
摘要:
The invention provides compounds for selectively inhibiting glycosidases, prodrugs of the compounds, and pharmaceutical compositions including the compounds or prodrugs of the compounds. The invention also provides methods of treating diseases and disorders related to deficiency or overexpression of O-GlcNAcase, accumulation or deficiency of O-GlcNAc.