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Drug-delivery endovascular stent and method for treating restenosis
专利权人:
Douglas R. Savage
发明人:
Douglas R. Savage,Ronald E. Betts
申请号:
US13023312
公开号:
US08252047B2
申请日:
2011.02.08
申请国别(地区):
US
年份:
2012
代理人:
摘要:
A radially expandable, endovascular stent designed for placement at a site of vascular injury, for inhibiting restenosis at the site, a method of using, and a method of making the stent. The stent includes a radially expandable body formed of one or more metallic filaments and a liquid-infusible mechanical anchoring layer attached to or formed in outer surface of the filaments. A drug coating in the stent is composed of a substantially polymer-free composition of an anti-restenosis drug, and has a substratum infused in the anchoring layer and a substantially continuous surface stratum of drug that is brought into direct contact with the vessel walls at the vascular site. Thus, the rate of release of the anti-restenosis drug from the surface stratum into said vascular site is determined solely by the composition of said drug coating.
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