Matthew Franco Myntti;Brian Vaccaro;Dana A. Oliver
发明人:
Matthew Franco Myntti,Dana A. Oliver,Brian Vaccaro
申请号:
US12429127
公开号:
US08802652B2
申请日:
2009.04.23
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Tissue and other body structures may be protected using a hydrated composition made from free-flowing substantially collagen-free rehydratable polysaccharide particles and rehydratable polysaccharide sponges. Rehydration of the particles without clumping may be carried out be dispersing the particles in a biocompatible water-miscible polar dispersant such as ethanol and combining the dispersion with sufficient aqueous solvent for the particles to convert them to a cohesive hydrogel. The hydrated composition may assist in returning an injured, inflamed or surgically repaired surface to a normal state, e.g., through one or more healing mechanisms such as modulation of an inflammatory response, phagocytosis, mucosal remodeling, reciliation or other full or partial restoration of normal function.