WANG, Shanger,BOOCK, Robert J.,DENNIS, Andrew Trinin,LEE, Ted Tang,SURI, Jeff T.,SZE, David,TAPSAK, Mark A.,ZHANG, Huashi,ZHOU, Jiong
申请号：
AU2020204319
公开号：
AU2020204319A1
申请日:
2020.06.29
申请国别(地区):
AU
年份:
2020
代理人:
摘要：
#$%^&*AU2020204319A120200716.pdf#####ABSTRACT Disclosed are devices for determining an analyte concentration (e.g., glucose). The devices comprise a sensor configured to generate a signal associated with a concentration of an analyte and a sensing membrane located over the sensor. The sensing membrane comprises a biointerface layer which interfaces with a biological fluid containing the analyte to be measured. The biointerface layer can comprises a biointerface polymer, wherein the biointerface polymer comprises polyurethane and/or polyurea segments and one or more zwitterionic repeating units. The sensing membrane can also comprise an enzyme layer, wherein the enzyme layer comprises an enzyme and a polymer comprising polyurethane and/or polyurea segments and one or more zwitterionic repeating units. The sensing membrane can also comprise a diffusion-resistance layer, which can comprise a base polymer having a lowest Tg of greater than -50C.
