Christopher Malcuit,Linda Lemieux,William Holmes,Pedro Huertas,Lucy Vilner
申请号：
US16597419
公开号：
US20200113938A1
申请日:
2019.10.09
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present invention provides improved methods for producing retinal pigmented epithelial (RPE) cells from human embryonic stem cells, human induced pluripotent stem (iPS), human adult stem cells, human hematopoietic stem cells, human fetal stem cells, human mesenchymal stem cells, human postpartum stem cells, human multipotent stem cells, or human embryonic germ cells. The RPE cells derived from embryonic stem cells are molecularly distinct from adult and fetal-derived RPE cells, and are also distinct from embryonic stem cells. The RPE cells described herein are useful for treating retinal degenerative conditions including retinal detachment and macular degeneration.
