A hazardous material containment bag and bag system for handling and transporting contaminated material or human remains is provided. The bag has a multi-layered structure that minimizes contamination by a chemical, biological, radiological and/or toxicological agent. The bag has an absorbent and/or adsorbent layer, which will help keep any hazardous components dissolved in bodily fluids immobilized inside the bag. The bag also has an active agent in at least one layer individually selected to neutralize or trap more than one type of contaminant. A bag system is also provided having an inner bag and a separate outer bag with the inner bag being a multi-layered structure having an absorbent material, which will help immobilize hazardous liquid, bodily fluids, and/or gases emanating from a contaminant enclosed in the inner bag. A method for using the hazardous material containment bag and bag system is also provided.
