Duncan Hiscock,Bente Elizabeth Arbo,Graeme Walter Mcrobbie,Bard Indrevoll,Rajiv Bhalla
申请号:
US13991260
公开号:
US20130251632A1
申请日:
2011.12.01
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention relates to radiopharmaceutical imaging in vivo of apoptosis and other forms of cell death. The invention provides PET imaging agents which target apoptotic cells via selective binding to the aminophospholipid phosphatidylethanolamine (PE), which is exposed on the surface of apoptotic cells. Also provided are pharmaceutical compositions, kits and methods of in vivo imaging.