MEERPOEL, LIEVEN,BACKX, LEO, JACOBUS, JOZEF,JAROSKOVA, LIBUSE,ROEVENS, PETER, WALTER, MARIA,VAN DER VEKEN, LOUIS, JOZEF, ELISABETH,VIELLEVOYE, MARCEL,LINDERS, JOANNES, THEODORUS, MARIA
申请号：
HK07107947.2
公开号：
HK1103582B
申请日:
2007.07.23
申请国别(地区):
HK
年份:
2012
代理人:
摘要：
The present invention is concerned with novel aryl piperidine or piperazine compounds substituted with certain 5-membered heterocycles having apoB secretion/MTP inhibiting activity and concomitant lipid lowering activity. The invention further relates to methods for preparing such compounds, pharmaceutical compositions comprising said compounds as well as the use of said compounds as a medicine for the treatment of hyperlipidemia, obesity and type II diabetes. The invention further relates to methods for preparing such compounds, pharmaceutical compositions comprising said compounds as well as the use of said compounds as a medicine for the treatment of atherosclerosis, pancreatitis, obesity, hypertriglyceridemia, hypercholesterolemia, hyperlipidemia, diabetes and type II diabetes.
