LEE, Seung-Hoon,이승훈,ΗΥΕΟΝ, Taeghwan,현택환,KIM, Chi Kyung,김치경,KANG, Dong-Wan,강동완,SOH, Min
申请号：
KRKR2016/004123
公开号：
WO2017/183746A1
申请日:
2016.04.20
申请国别(地区):
WO
年份:
2017
代理人:
摘要：
The present invention relates to a pharmaceutical composition for treating atraumatic intracerebral hemorrhage, comprising a ceria nanocomposite. The pharmaceutical composition comprising a ceria nanocomposite, of the present invention, efficiently reaches the inside of the cytoplasm through the cell membrane and exhibits excellent antioxidative and antiinflammatory effects in the hematoma and the surrounding region thereof. Therefore, the pharmaceutical composition can be usefully used for the treatment of atraumatic intracerebral hemorrhage.La présente invention concerne une composition pharmaceutique pour le traitement dune hémorragie intracérébrale atraumatique, comprenant un nanocomposite doxyde de cérium. La composition pharmaceutique comprenant un nanocomposite doxyde de cérium, de la présente invention, atteint efficacement lintérieur du cytoplasme à travers la membrane cellulaire et présente dexcellents effets antioxydants et anti-inflammatoires dans lhématome et la région entourant celui-ci. Par conséquent, la composition pharmaceutique peut être utilement employée pour le traitement dune hémorragie intracérébrale atraumatique.본 발명은 세리아 나노복합체를 포함하는 비외상성 두개내 출혈 치료용 약학적 조성물에 관한 것으로서, 본 발명의 세리아 나노복합체를 포함하는 약학적 조성물은, 세포막을 통과하여 세포질 내에 효율적으로 도달해, 혈종 및 혈종 주변 부위에서 우수한 항산화 및 항염증 효과를 나타내므로, 비외상성 두개내 출혈 치료에 유용하게 사용될 수 있다.
