The invention relates to a method for introducing biologically active substances into the brain, by the nasal introduction of a pharmaceutical composition consisting of biologically and therapeutically active substances together with membrane-active substances, hydrogen peroxide and nitrogen monoxide and their sources which remain in the nasal cavity in a disintegrated state, with only the pharmacologically active substances being transferred. The method is characterised in that the pharmaceutical composition is introduced nasally once or multiple times in complete or partial doses, that the time interval between introductions is between 3 and 180 seconds, preferably 60 seconds and that the drug dose is between 2 and 100 times smaller than the pharmaceutically predetermined dose.