Disclosed herein is a use of phosphoglycerate kinase (PGK) for the preparation of a medicament for the enhancement of the outgrowth of neurite. Based on the enhancing effect, PGK is capable of being used alone or in combination with an active component to treat a subject suffering from immunological disease.本揭示內容是關於一種磷酸甘油酯激酶之用途,其係用以製備一藥物以增加神經突的生長。基於此功效,磷酸甘油酯激酶可單獨使用或與一活性成分合併使用,以治療罹患神經性疾病之個體。