Mukund Mehrotra;Yonghong Song;Shawn M. Bauer;Qing Xu;Anjali Pandey;Jack W. Rose;Wolin Huang
发明人:
Shawn M. Bauer,Jack W. Rose,Yonghong Song,Qing Xu,Mukund Mehrotra,Wolin Huang,Anjali Pandey
申请号:
US12775358
公开号:
US08367689B2
申请日:
2010.05.06
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention is directed to compounds of formula I and tautomers and pharmaceutically acceptable salts thereof which are selective inhibitors of JAK. The present invention is also directed to intermediates used in making such compounds, the preparation of such a compound, pharmaceutical compositions containing such a compound, methods of inhibition JAK activity, and methods to prevent or treat a number of conditions mediated at least in part by JAK activity.