Shawn M. Bauer,Jack W. Rose,Yonghong Song,Qing Xu,Mukund Mehrotra,Wolin Huang,Anjali Pandey
申请号:
US13717569
公开号:
US08853230B2
申请日:
2012.12.17
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present invention is directed to compounds of formula I and tautomers and pharmaceutically acceptable salts thereof which are selective inhibitors of JAK. The present invention is also directed to intermediates used in making such compounds, the preparation of such a compound, pharmaceutical compositions containing such a compound, methods of inhibition JAK activity, and methods to prevent or treat a number of conditions mediated at least in part by JAK activity.