Humanized anti-IL-10 antibodies for the treatment of systemic lupus erythematosus (SLE)

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专利权人:

Frank Osterroth;Christoph Bruecher;Niklas Czeloth;Marcus Gutscher;Christoph Uherek;Peter Röttgen;Chantal Zuber;Andrea Wartenberg-Demand;Benjamin Daelken;André Engling;Judith Wessels-Kranz

发明人:

Frank Osterroth,Christoph Uherek,Christoph Bruecher,Peter Röttgen,Benjamin Daelken,André Engling,Chantal Zuber,Niklas Czeloth,Andrea Wartenberg-Demand,Marcus Gutscher,Judith Wessels-Kranz

申请号：

US13512780

公开号：

US08852871B2

申请日:

2010.11.30

申请国别(地区):

US

年份:

2014

代理人:

摘要：

Provided is a humanized or chimeric antibody or fragment thereof capable of binding to interleukin-10 (Th-10), wherein said antibody or fragment thereof is capable of being administered to a subject in the absence of an intolerable increase in the level of pro-inflammatory cytokines. Further provided are methods of treatment involving the use of the antibody or fragment thereof.

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中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/