HUMANIZED ANTI-IL-10 ANTIBODIES FOR THE TREATMENT OF SYSTEMIC LUPUS ERYTHEMATOSUS (SLE)

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专利权人:

BIOTEST AG

发明人:

OSTERROTH, FRANK,UHEREK, CHRISTOPH,BRUECHER, CHRISTOPH,RÖTTGEN, PETER,DAELKEN, BENJAMIN,ENGLING, ANDRÉ,ZUBER, CHANTAL,CZELOTH, NIKLAS,WARTENBERG-DEMAND, ANDREA,GUTSCHER, MARCUS,WESSELS-KRANZ, JUDITH

申请号：

SG2012038626

公开号：

SG181069A1

申请日:

2010.11.30

申请国别(地区):

SG

年份:

2012

代理人:

摘要：

Provided is a humanized or chimeric antibody or fragment thereof capable of binding to interleukin-10 (IL-10), wherein said antibody or fragment thereof is capable of being administered to a subject in the absence of an intolerable increase in the level of pro-inflammatory cytokines. Further provided are methods of treatment involving the use of the antibody or fragment thereof.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/