John Paul Kilburn,Henrik Sune Andersen,Gita Camilla Tejlgaard Kampen
申请号:
US11665103
公开号:
US08138342B2
申请日:
2005.10.12
申请国别(地区):
US
年份:
2012
代理人:
摘要:
A novel class of compounds of the general formula (I), their use in therapy, pharmaceutical compositions comprising the compounds, as well as their use in the manufacture of medicaments are described. The present compounds modulate the activity of 11 β-hydroxy-Steroid dehydrogenase type 1 (11βHSD1) and are accordingly useful in the treatment of diseases in which such a modulation is beneficial, e.g. the metabolic syndrome.