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11-Beta-Hydroxysteroid Dehydrogenase Type 1 Active Compounds
专利权人:
Soren Ebdrup
发明人:
Soren Ebdrup,Henrik Sune Andersen
申请号:
US13236131
公开号:
US20120004209A1
申请日:
2011.09.19
申请国别(地区):
US
年份:
2012
代理人:
摘要:
A novel class of compounds of the general formula (I), their use in therapy, pharmaceutical compositions comprising the compounds, as well as their use in the manufacture of medicaments are described. The present compounds modulate the activity of 11β-hydroxy-steroid dehydrogenase type 1 (11βHSD1) and are accordingly useful in the treatment of diseases in which such a modulation is beneficial, e.g. the metabolic syndrome.
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