Kuebelbeck, Armin,Weigandt, Markus,Larbig, Gregor,Hanefeld, Andrea
申请号:
AU2009270468
公开号:
AU2009270468B2
申请日:
2009.07.13
申请国别(地区):
AU
年份:
2014
代理人:
摘要:
The invention relates to ultra-small, monodisperse nanoparticles of silicon dioxide with at least one antigen attached to their surface. The nanoparticles can be used for the immunoprophylaxis or immunotherapy of cancer. The invention also provides a method of targeting antigens at antigen-presenting cells and of activating the immune system, the efficiency of targeting and/or immune activation being adjusted via the particle characteristics. The invention also relates to methods of active and passive immunization of a mammal.