ANDREA HANEFELD,ARMIN KUEBELBECK,GREGOR LARBIG,MARKUS WEIGANDT
申请号：
BRPI0915788
公开号：
BRPI0915788A2
申请日:
2009.07.13
申请国别(地区):
BR
年份:
2015
代理人:
摘要：
The invention relates to ultrasmall, monodisperse nanoparticles comprising silicon dioxide to the surface of which at least one antigen is attached. The nanoparticles can be used for the immunoprophylaxis or immunotherapy of cancer. The invention also relates to a method for the targeting of antigens at antigen-presenting cells and for the activation of the immune system, where the efficiency of targeting and/or immunoactivation are set via the particle characteristics. The invention also relates to a method for the active and passive immunization of a mammal.
