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PHARMACEUTICAL COMBINATION AND ITS APPLICATION
专利权人:
ЛАБОРАТОРИОС СЕНОСИАЙН С.А. ДЕ С.В. (MX)
发明人:
СЕНОСИАЙН ПЕЛЕЗ Хуан Пабло (MX),АРСОЛА ПАНИАГВА Анхелика (MX),ГАРСИЯ-САЛЬГАДО ЛОПЕС Энрике Рауль (MX)
申请号:
RU2012151921/15
公开号:
RU2012151921A
申请日:
2011.04.28
申请国别(地区):
RU
年份:
2014
代理人:
摘要:
1. A pharmaceutical combination containing ibuprofen and L-arginine, in which the mass ratio of ibuprofen / L-arginine is from 1.6 to 5.6, with the exception of a value of approximately 1.97.2. A pharmaceutical combination containing ibuprofen and L-arginine, in which the mass ratio of ibuprofen / L-arginine is from 3.26 to 5.0.3. The combination according to claim 1 or 2, in which the mass ratio of ibuprofen / L-arginine is approximately 3.26.4. The combination according to claim 1 or 2, in which the mass ratio of ibuprofen / L-arginine is approximately equal to 5.0.5. A solid pharmaceutical composition comprising a pharmaceutical combination according to claims 1-3 or 4 and pharmaceutically acceptable excipients. 6. The pharmaceutical composition according to claim 5, intended for oral administration. The pharmaceutical composition according to claim 5, which is in the form of a suspension, pill, tablet, granule, powder or capsule. A method for treating pain, swelling and / or heat, comprising administering the pharmaceutical composition of claim 5.9. The use of the combination according to claims 1-3 or 4 as an antipyretic, anti-inflammatory and / or analgesic substance. 10. Use of a combination according to claims 1-3 or 4 as an anesthetic. 11. The combination according to claims 1 to 3 or 4, in which ibuprofen is the enantiomer of (+) S-ibuprofen. A pharmaceutical combination containing (+) S-ibuprofen and L-arginine, in which the mass ratio of (+) S-ibuprofen / L-arginine is from 0.8 to 4.5.13. The combination of claim 12, wherein the weight ratio of (+) S-ibuprofen / L-arginine is approximately 2.12.14. A pharmaceutical composition comprising a pharmaceutical combination according to claim 12 or 13 and pharmaceutically acceptable excipients. Pharmaceutical1. Фармацевтическая комбинация, содержащая ибупрофен и L-аргинин, в которой массовое соотношение ибупрофен/L-аргинин составляет от 1,6 до 5,6, за исключением величины, приблизительно равной 1,97.2. Фармацевт
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