Iontcho Radoslavov Vlahov,Christopher Paul Leamon,Yu Wang
申请号：
US12739579
公开号：
US09187521B2
申请日:
2008.10.23
申请国别(地区):
US
年份:
2015
代理人:
摘要：
Processes are described for the preparation of tubulysins. The processes are useful for preparing predetermined mixtures of tubulysins, preparing single tubulysins from mixtures of tubulysins, and for converting one tubulysin into a different tubulysin. The tubulysins described herein are useful in treating diseases and disease states that include pathogenic cell populations.
