#$%^&*AU2012261568A120130110.pdf#####COMPOSITIONS AND METHODS FOR THE TREATMENT OR PREVENTION OF CHEMORESISTANT NEOPLASIA Abstract of the Disclosure 5 The invention generally features compositions and methods useful for the treatment and diagnosis of a neoplasia in a subject. In particular, the invention provides therapeutic compositions that decrease the expression of an Nfr2 nucleic acid molecule or polypeptide for the treatment of a neoplasia, such as a chemoresistant neoplasia, in a subject. 10