An IRE guidance collar assembly used to support an IRE needle or other ablation-type devices, comprising a guidance collar eye component and a guidance collar tube component. The collar eye component is movable, and slides freely along the guidance collar tube. This provide rigidity to the IRE needle while allowing various depths of insertion. The IRE needle body is seated in the receiving end of the guidance collar tube, with the needle inserted into and through the tube end of the guidance collar tube. One end of the guidance collar eye component snaps onto and fits over the tube end of the guidance collar tube, while the other end has a needle holder through which the IRE needle is inserted. The collar eye end slides along the tube end of the guidance collar tube, moving the needle holder of the collar end close to or away from the end of the guidance collar tube, as desired.