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Compounds for Reducing Glucocorticoids, and Methods of Treatment Thereof
专利权人:
发明人:
Tony Durst,Zulfiquar Merali,Christian Cayer,John Thor Arnason,John Douglas Baker
申请号:
US14441620
公开号:
US20150272922A1
申请日:
2013.11.08
申请国别(地区):
US
年份:
2015
代理人:
摘要:
A method for reducing glucocorticoids in an animal in need thereof comprising the use of compounds of the formula (I), wherein the definitions for R′, R1-R11 and n are as disclosed in the description. The compounds of formula (I) are for the treatment or prevention of a glucocorticoid-related disorder for maintaining bone density, maintaining and improving the immune system, treating Cushings syndrome, treating obesity, improving reproduction efficiency, treating metabolic disorder, treating hypertension, treating hyperglycemia, treating insulin resistance, treating type 2 diabetes, and/or aiding in cancer and immune therapies
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