MABIMMUNE DIAGNOSTICS AG;NEURIMMUNE HOLDING AG;UNIVERSITY OF ZURICH
发明人:
BROKOPP, CHAD,GRIMM, JAN,COMBALUZIER, BENOIT,GOERANSON, MAREIKE,LOHMANN, CHRISTINE,HOERSTRUP, SIMON,NITSCH, ROGER
申请号：
CA2973040
公开号：
CA2973040A1
申请日:
2016.01.11
申请国别(地区):
CA
年份:
2016
代理人:
摘要：
Provided are novel human-derived antibodies specific for Fibroblast Activation Protein (FAP), preferably capable of selectively inhibiting the enzymatic activity of FAP, as well as methods related thereto. In addition, methods of diagnosing and/or monitoring diseases and treatments thereof which are associated with FAP are provided. Assays and kits related to antibodies specific for FAP are also disclosed. The novel anti-FAP antibodies can be used in pharmaceutical and diagnostic compositions for FAP-targeted immunotherapy and diagnostics.
