Mabimmune Diagnostics AG;Neurimmune Holding AG;University of Zurich
发明人:
Chad BROKOPP,Jan GRIMM,Benoit COMBALUZIER,Mareike GOERANSON,Christine LOHMANN,Simon HOERSTRUP,Roger NITSCH
申请号：
US15541998
公开号：
US20170369592A1
申请日:
2016.01.11
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Provided are novel human-derived antibodies specific for Fibroblast Activation Protein (FAP), preferably capable of selectively inhibiting the enzymatic activity of FAP, as well as methods related thereto. In addition, methods of diagnosing and/or monitoring diseases and treatments thereof which are associated with FAP are provided. Assays and kits related to antibodies specific for FAP are also disclosed. The novel anti-FAP antibodies can be used in pharmaceutical and diagnostic compositions for FAP-targeted immunotherapy and diagnostics.
