The present invention concerns methods for inducing an immune response to an antigen in a patient for treating human disease by administering an immunogenic composition wherein said patient is selected in a patient population of interest. The present invention further concerns methods for determining whether a subject is or is not susceptible to developing a prophylactic or therapeutic immune response after such treatment.本發明係關於藉由投與免疫原性組合物而在病患中誘導對抗原之免疫反應以治療人類疾病的方法,其中在所關注之病患群體中選擇該病患。本發明另外係關於測定個體在此治療之後是否易產生預防性或治療性免疫反應之方法。