A compound of formula (I) ** Formula ** or an enantiomer, a diastereomer, a tautomer, a salt or a solvate thereof, wherein: A is - (CH2) m-R2, -CH (R26) - R2, - (CH2) n-1-O-R2, - (CH2) n-1-NR25-R2, -CH (R26) -CO2-R2, or - (CH2) n-1-NR25-CO2-R2 ； R1 is C1-10 alkyl substituted with 1-2 -OH, C1-10 haloalkyl, C2-12 alkenyl or C3-10 cycloalkyl, where the cycloalkyl can be substituted with 0-2 R13； or R1 is ** Formula ** any one of which may be substituted with 0-2 R13； R2 is phenyl, cyclopentyl, cyclohexyl, pyridinyl, pyrazinyl, pyridazinyl, pyrimidinyl, piperidinyl, pyridinone, pyrrolidinyl, tetrahydropyrans, or thiazolyl, either of which is substituted with 0-2 R2a； R2a, at each occurrence, is independently H, -OH, F, Cl, Br, I, C1-10 alkyl, C1-10 alkoxy, C1-10 haloalkyl, C3-10 cycloalkyl, C2-12 alkenyl, C2-12 alkynyl , C6-10 aryl, a 4- to 12-membered heteroaryl, a 4 to 12-membered heterocyclyl, a 4- to 12-membered heteroaryl-C1-alkyl, -CN, -NO2, - (CH2) m-SO2R14, - NR14SO2R14,>； = O, - CONR14R14, - (CH2) mSO2NR14R14, - (CH2) mNR14SO2R14, - (CH2) n-NR14SO2NR14R14, -NR14SO2N14R14, -NR14R14, -NR14R14, -NR14R14, -R -CO2R14, - NR14R14, NR14CONR14R14, -C (>； = NOR14) NR14R14, CONR14OR14 or -NCOR14, where the alkyl, cycloalkyl, alkenyl, alkoxy, aryl, heteroaryl and heterocyclyl can be substituted with 0-2 R14a, and heteroaryl and the heterocyclyl consist of carbon atoms and 1, 2, 3, or 4 heteroatoms independently selected from the group consisting of N, S, or O； R3 is phenyl, pyridinyl, pyrimidinyl, or dihydropyran or tetrahydropyran, any of which may be substituted with 0-1 R3a； R3a is halo, CN, NH2, -O-C1-3alkyl or morpholinyl； R13, at each occurrence, is independently H, -OH, F, Cl, Br, I, CN, C1-10 alkyl, C1-10 alkoxy, C1-10 haloalkyl, C3-10 cycloalkyl, C2-12 alkenyl, C2 alkynyl -12, C6-10 aryl, a 4- to 12-membered heteroaryl, a 4- to 12-membered heterocyclyl, a 4- to 12-membered C1-10 heteroaryl-alkyl, -CN, -NO2, - (CH2) m-SO2R14 , -NR14SO2R14,>； = O, -CONR14R14,
