PROBLEM TO BE SOLVED: To provide a medicinal composition containing a pyrazole compound having a CB1 receptor-antagonizing action as an active ingredient.SOLUTION: This medicinal composition comprises a compound represented by general formula [I] (wherein, R1 and R2 are a substituted or non-substituted aryl group or the like R3 is an alkyl group, or the like E is amide group, carbamoyl group, or the like, or a substituent containing a heterocyclic compound such as furan, pyridine, morpholine, oxadiazole, or thiadiazole) or its pharmacologically acceptable salt as an active ingredient.COPYRIGHT: (C)2009,JPO&INPIT【課題】CB1受容体拮抗作用を有するピラゾール化合物を有効成分としてなる医薬組成物を提供する。【解決手段】一般式[I]:〔式中、R1及びR2は置換又は非置換アリール基等、R3はアルキル基等、Eはアミド基、カルバモイル基等、又はフラン、ピリジン、モルホリン、オキサジアゾール、チアジアゾール等の複素環化合物等を含む置換基を表す。〕で示される化合物又はその薬理的に許容し得る塩を有効成分としてなる医薬組成物。【選択図】なし
