It refers to a variety of formulated compounds (I), of which the methyl ring is pyridine, pyridine, among others； the second ring is C3-C6 ring, cquilo, arilo, C6-C14, C1； R1 is hydroxyl, C1-C8 tar, or Alcoy C1-C8； R2 is CN, halogen, hydroxyl, etc.； R3, R4 and R5 are halogen, CN, C1-C8 tar, etc.； RA and Rb are each. Either C1-C8, or L is absent, or X - (crxry) T -,Where x is or, among other things, RX and ry are h, C1-C8 tar, C1-C8 hydroxyl compounds, etc.； N, Q and T are 0 to 3； m and P are 0 to 2； X, y and Z are one junction point. The most popular compounds were n - (4 - (3 - (4-chlorophenyl) pyridine-2-phenyl) - 2 - (4 - (1-difluoropropyl) phenyl； 2 - (4 - (1,1-difluoropropyl) phenyl) - N - (4 - (3 - (2-fluorophenyl) pyridin-2-il) phenyl. He also mentioned a pharmaceutical composer These compounds are modulators of the huerfan gamma receptor associated with the retina (ROR gamma T) and are useful in the treatment of rheumatoid arthritis, psychosis and asthma.SE REFIERE A COMPUESTOS HETEROCICLOS DE FORMULA (I) DONDE EL ANILLO A ES PIRAZINA, PIRIDINA, ENTRE OTROS； EL ANILLO B ES CICLOALQUILO C3-C6, ARILO C6-C14, ENTRE OTROS； R1 ES HIDROXILO, ALQUILO C1-C8 O ALCOXI C1-C8； R2 ES CN, HALOGENO, HIDROXILO, ENTRE OTROS； R3, R4 Y R5 SON CADA UNO HALOGENO, CN, ALQUILO C1-C8, ENTRE OTROS； Ra Y Rb SON CADA UNO H O ALQUILO C1-C8； L ESTA AUSENTE O ES -X-(CRxRy)t-, EN DONDE X ES O, ENTRE OTROS； Rx Y Ry SON CADA UNO H, ALQUILO C1-C8, HIDROXIALQUILO C1-C8, ENTRE OTROS； n, q Y t SON DE 0 A 3； m Y p SON DE 0 A 2； x, y Y z SON UN PUNTO DE UNION. SON COMPUESTOS PREFERIDOS: N-(4-(3-(4-CLOROFENIL)PIRAZIN-2-IL)FENIL)-2-(4-(1,1-DIFLUOROPROPIL)FENIL)ACETAMIDA； 2-(4-(1,1-DIFLUOROPROPIL)FENIL)-N-(4-(3-(2-FLUOROFENIL)PIRAZIN-2-IL)FENIL)ACETAMIDA； ENTRE OTROS. TAMBIEN SE REFIERE A UNA COMPOSICION FARMACEUTICA. DICHOS COMPUESTOS SON MODULADORES DEL RECEPTOR HUERFANO GAMMA T ASOCIADO CON RETINOIDES (ROR GAMMA T) SIENDO UTILES EN EL TRATAMIENTO DE ARTRITIS REUMATOIDE, PSORIASIS, ASMA
