THE BROAD INSTITUTE INC.;MASSACHUSETTS INSTITUTE OF TECHNOLOGY;PRESIDENT AND FELLOWS OF HARVARD COLLEGE;THE BRIGHAM AND WOMEN'S HOSPITAL, INC.
发明人:
Aviv Regev,Vijay Kuchroo,Hongkun Park,Nir Yosef,Alexander K. Shalek,Jellert Gaublomme,Nicole C. Joller,Chuan Wu,Ana Carrizosa Anderson
申请号：
US14837702
公开号：
US20150361396A1
申请日:
2015.08.27
申请国别(地区):
US
年份:
2015
代理人:
摘要：
This invention relates generally to compositions and methods for identifying the regulatory network that modulates, controls or otherwise influences T cell balance, for example, Th17 cell differentiation, maintenance and/or function, as well compositions and methods for exploiting the regulatory network that modulates, controls or otherwise influences T cell balance in a variety of therapeutic and/or diagnostic indications. This invention also relates generally to identifying and exploiting target genes and/or target gene products that modulate, control or otherwise influence T cell balance in a variety of therapeutic and/or diagnostic indications.
