THE BROAD INSTITUTE, INC.;THE BRIGHAM AND WOMEN'S HOSPITAL, INC.;PRESIDENT AND FELLOWS OF HARVARD COLLEGE;MASSACHUSETTS INSTITUTE OF TECHNOLOGY
发明人:
KUCHROO, VIJAY,REGEV, AVIV,GAUBLOMME, JELLERT,LEE, YOUJIN,SHALEK, ALEXANDER K.,WANG, CHAO,YOSEF, NIR,PARK, HONGKUN
申请号：
CA2940653
公开号：
CA2940653A1
申请日:
2015.02.26
申请国别(地区):
CA
年份:
2015
代理人:
摘要：
This invention relates generally to compositions and methods for identifying the regulatory network that modulates, controls or otherwise influences T cell balance, for example, Th17 cell differentiation, maintenance and/or function, as well, compositions and methods for exploiting the regulatory network that modulates, controls or otherwise influences T cell balance in a variety of therapeutic and/or diagnostic indications. This invention also relates generally to identifying and exploiting target genes and/or target gene products that modulate, control or otherwise influence T cell balance in a variety of therapeutic and/or diagnostic indications.
