SALANTI, ALI,THEANDER, THOR GRUNDTVIG,DAUGAARD, MADS,NIELSEN, MORTEN,DAHLBACK, MADELEINE,CLAUSEN, THOMAS MANDEL
申请号：
CA2861051
公开号：
CA2861051A1
申请日:
2013.02.08
申请国别(地区):
CA
年份:
2013
代理人:
摘要：
The present invention relates to functional binding fragments comprising the minimal binding fragments of VAR2CSA, to antibodies against such binding fragments of VAR2CSA, nucleic acids encoding such fragments of VAR2CSA as well as methods for their production. The invention further relates to conjugates and fusion proteins of VAR2CSA polypeptides including the minimal binding fragments and their use, in particular in the treatment of conditions associated with expression of chondroitin sulfate A (CSA), such as an inappropriate expression of chondroitin sulfate A (CSA).
