Memorial Sloan-Kettering Cancer Center;The General Hospital Corporation
发明人:
申请号:
EP15858791.5
公开号:
EP3218413A4
申请日:
2015.11.12
申请国别(地区):
EP
年份:
2018
代理人:
摘要:
Described herein are antibodies that bind chondroitin sulfate proteoglycan 4 (CSPG4) and, in particular, chimeric and humanized anti-CSPG4 antibodies and fragments thereof. Also provided herein are methods of using individual humanized antibodies or compositions thereof for the detection, prevention, and/or therapeutic treatment of CSPG4-related diseases, in particular, melanoma.