XIE JI,WU GEORGE,LAMBERSON JOSEPH,POIRIER MARC,CHEN FRANK
申请号:
NZ61730012
公开号:
NZ617300A
申请日:
2012.05.02
申请国别(地区):
NZ
年份:
2015
代理人:
摘要:
Disclosed is a processes for the preparation of compounds of Formula (I) (including boceprevir) that are useful as inhibitors of the hepatitis C virus (HCV) NS3 protease and have application in the treatment of conditions caused by HCV. In particular, the present invention relates to oxidation processes useful for preparing compounds of Formula (I) and related compounds, including pharmaceutically acceptable salts, hydrates and solvates thereof, and including stereoisomers thereof.