Ramanadham Jyothi Prasad,Bhujanga rao Adibhatla Kali Satya,Nannapaneni Venkaiah Chowdary
申请号：
US12672191
公开号：
US08349855B2
申请日:
2007.09.11
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The present invention relates to three novel crystalline forms of Erlotinib hydrochloride and method of preparation thereof. Erlotinib hydrochloride is N-(3-ethynylphenyl)-6,7-bis(2-methoxy ethoxy)-4-quinazolinamine hydrochloride of formula-(I).The present invention provides stable novel crystalline forms of Erlotinib hydrochloride designated as Form-M, Form-N and Form-P, and processes for the preparation of the same. Erlotinib hydrochloride can be used as medicament for the treatment of hyperproliferative disorders, such as cancers, in humans.
