PROBLEM TO BE SOLVED: To provide a tablet that can retain a principal ingredient even after being formulated for a long period of time by reducing unstabilization to such as pressure, impact, friction and heating applied when formulating candesartan cilexetil containing solid preparation which causes the reduction in storage stability of the principal ingredient after formulation by the influence of such as the impact, the friction and the heating.SOLUTION: In the solid preparation produced by using the candesartan cilexetil and an additive generally used, water equivalent to 2-10 wt.% of the total weight of a composition for formulating the solid preparation is contained for the formulation.COPYRIGHT: (C)2013,JPO&INPIT【課題】カンデサルタンシレキセチル含有固形製剤の製剤時に加えられる圧力、衝撃、摩擦、加熱等の影響によって製剤化後の主剤の保存安定性が低下するので、その衝撃、摩擦、加熱等に対する不安定化を軽減し、製剤化後も主薬を長期間安定に保持できる錠剤を提供すること。【解決手段】カンデサルタンシレキセチルと通常用いられる添加剤を用いて製造する固形製剤において、その製剤化用組成物の全重量の2~10重量%に相当する水分を含有させて製剤化することによって上記課題を解決した。【選択図】なし
