Cancer therapeutic agent comprising a proliferative adenovirus vector containing a Survivin promoter as an active ingredient

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专利权人:

小財;健一郎

发明人:

神囿 純一,永野 聡,小戝 健一郎

申请号：

JP2006513972

公开号：

JP5574284B2

申请日:

2005.05.23

申请国别(地区):

JP

年份:

2014

代理人:

摘要：

It is intended to provide a drug to be used in gene therapy which specifically targets abnormal cells such as tumor cells and destroys the same for healing. Namely, a drug comprising, as the active ingredient, a proliferative vector which contains a Survivin promoter proliferating depending on the expression of Survivin. This drug may be used in order to treat tumor. In this drug, use may be made of an adenovirus as the vector. In the adenovirus of this drug, an endogenous promoter of an E1A domain may be substituted with a Survivin promoter.

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