HEMMINKI, AKSELI,KANERVA, ANNA,CERULLO, VINCENZO,PESONEN, SARI
申请号：
CA2748180
公开号：
CA2748180C
申请日:
2009.12.21
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
The present invention relates to the fields of life sciences and medicine.Specifically, the invention relates to cancertherapies. More specifically, the present invention relates to oncolyticadenoviral vectors and cells and pharmaceutical compositionscomprising said vectors. The present invention also relates to a use of saidvectors in the manufacture of a medicament fortreating cancer in a subject and a method of treating cancer in a subject.Furthermore, the present invention relates to methods ofproducing GM-CSF in a cell and increasing tumor specific immune response in asubject, as well as uses of the oncolytic adenoviralvector of the invention for producing GM-CSF in a cell and increasing tumorspecific immune response in a subject.
