Horlick, Robert A.,King, David J.,McKnight, Andrew John
申请号：
AU2015204674
公开号：
AU2015204674A1
申请日:
2015.01.09
申请国别(地区):
AU
年份:
2016
代理人:
摘要：
The invention relates to an isolated immunoglobulin heavy chain polypeptide and an isolated immunoglobulin light chain polypeptide that bind to interleukin-33 (IL-33). The invention provides an IL-33-binding agent that comprises the aforementioned immunoglobulin heavy chain polypeptide and immunoglobulin light chain polypeptide. The invention also provides related vectors, compositions, and methods of using the IL-33-binding agent to treat a disorder in a mammal that is responsive to IL-33 inhibition.
