Robert A. Horlick,David J. King,Andrew John McKnight
申请号：
US15110724
公开号：
US10059764B2
申请日:
2015.01.09
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The invention relates to an isolated immunoglobulin heavy chain polypeptide and an isolated immunoglobulin light chain polypeptide that bind to interleukin-33 (IL-33). The invention provides an IL-33-binding agent that comprises the aforementioned immunoglobulin heavy chain polypeptide and immunoglobulin light chain polypeptide. The invention also provides related vectors, compositions, and methods of using the IL-33-binding agent to treat a disorder in a mammal that is responsive to IL-33 inhibition.
